Majalah Ilmu Faal Indonesia
ISSN 0215-1995
Vol. 9 / No. 3 / Published : 2010-06
Order : 12, and page :217 - 221
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Original Article :
Effect of black soybean extract supplementation in low density lipoprotein level of rats (rattus norvegicus) with high fat diet
Author :
- Setyawati Sigit*1
- Eduardus Bimo Aksono H.P*2
- Ratna Damayanti*3
- Retno Bijanti*4
- Intan Herwiyarirasanta*5
- Herman Setyono*6
- Departemen Ilmu Kedokteran Dasar Veteriner Fakultas Kedokteran Hewan Universitas Airlangga
- Departemen Ilmu Kedokteran Dasar Veteriner Fakultas Kedokteran Hewan Universitas Airlangga
- Departemen Ilmu Kedokteran Dasar Veteriner Fakultas Kedokteran Hewan Universitas Airlangga
- Departemen Ilmu Kedokteran Dasar Veteriner Fakultas Kedokteran Hewan Universitas Airlangga
- Mahasiswa FKH Unair
- Departemen Produksi Ternak FKH Unair
Abstract :
Research on the effect of black soybean extract feeding on Low Density Lipoprotein (LDL) level of rat has been done. Twenty four male white Wistar rats (Rattus norvegicus) divided into three groups randomly, were given high fat diet to induce hypercholesterolemic condition. Hypercholesterolemic condition was gained after feeding high fat diet content for 4 weeks (a month). After a month the first group (P0) was given high fat diet and aquadest treatment, the second group (P1) was given high fat diet and black soybean extract feeding, and the third group (P2) was given standard diet and black soybean extract feeding. After three weeks of treatment, the blood was taken out from the heart and then LDL level in blood serum was measured. The result showed that black soybean milk feeding has decreasing LDL blood serum level of the rats significantly (p<0,05).
Keyword :
Black soybean extract, high fat diet, low density lipoprotein,
References :
Kirk, Sutherland, Wang, Chartz and Le Beauf,(1998) Dietary Isoflavone Reduce Plasma Cholesterol And Atherosclerosis in Mice 128: 954-959 : Journal Nutrition
Hess, T., Philip, K., and Thomas, J. M,(2006) Association Between Atherosclerosis and Glomerulopathy in Dogs Vol : 4 Number 3 : Intern. J. Appl. Res. Vet. Med
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